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The molecular genetics underlying basal cell carcinoma pathogenesis and links to targeted therapeutics
30 August 2010
Julie K. Iwasaki, Divya Srivastava, Ronald L. Moy, Henry J. Lin, David J. Kouba
Mutations in the sonic hedgehog signaling pathway play a key role in the development of basal cell carcinomas. Specifically, mutations in the PTCH1 (also known as PTCH or PTC1) and SMO genes cause tum...
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Prospective study of wound infections in Mohs micrographic surgery using clean surgical technique in the absence of prophylactic antibiotics
30 August 2010
Heather D. Rogers, Edward B. Desciak, Rebecca P. Marcus, Shuang Wang, Julian MacKay-Wiggan, Yehuda D. Eliezri
Background: Mohs micrographic surgery (MMS) has a low rate of surgical site infection (SSI) without the use of prophylactic antibiotics. In the studies to date, there has been variation in the steps t...
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Medical missions: A therapeutic primer
30 August 2010
Alan S. Boyd
Trips abroad to underdeveloped countries for the purpose of providing dermatologic care (medical missions), while both exciting and gratifying, require planning and forethought. What do I bring? What ...
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Cutaneous lupus erythematosus: Update of therapeutic options: Part II
30 August 2010
Annegret Kuhn, Vincent Ruland, Gisela Bonsmann
In the first part of the review, topical agents and first-line systemic treatment options for cutaneous lupus erythematosus were discussed whereas in the second part, recent information on efficacy, d...
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The association of dermatitis herpetiformis and systemic lupus erythematosus
26 August 2010
Tracie L. Kurano, Christopher A. Lum, Allan K. Izumi
Dermatitis herpetiformis (DH) is an immune-mediated cutaneous disease occasionally associated with celiac disease, but rarely associated with systemic lupus erythematosus (SLE). The combination of DH ...
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